Preliminary Topics

UTERINE TRANSPLANTATION

  • Technical surgical consideration
  • Results of surgery
  • Perinatal pitfall and results
  • Artificial Uterus – state of the art

OVARIAN STIMULATION

  • Ovarian stimulation – lessons from over 30 years of IVF
  • Innovative stimulation
  • How to assess the polycystic ovary: An ultrasound and AMH update
  • Screening and management of hypothyroidism

CURRENT MANAGEMENT OF UTERINE FIBROID

  • Evidence base fibroids removal prior to IVF
  • When to use hysteroscopy and when to use laparoscopy for removal
  • SPRMs mechanism of action on fibroids
  • Medical treatment of fibroids in infertile women

PRESERVATION OF FERTILITY

  • Medical protection of gonadal damage
  • Ovarian tissue transplantation techniques and results
  • Ovarian tissue freezing- the lab perspectives
  • The potential of spermatogonial stem cells as target for fertility preservation in boys

PGS/PGD

  • Debate: Mosaicism- some PGS labs report mosaicism and others not. Why? Should we transfer mosaic embryos? What are the legal risks?
  • Debate: PGS
    All embryos should be tested
    No embryo should be tested

ROLE OF HYSTEROSCOPY IN INFERTILITY

  • role of hysteroscopy before IVF. Diagnosis and treatment of Chronic Endometritis
  • Role of Hysteroscopy in proximal tubal occlusions
  • Medical and Surgical therapy for adenomyosis
  • Uterine adenomyosis: Hysteroscopic and laparoscopic approaches

ENDOMETRIOSIS

  • Diagnosis of Endometriosis
  • Deep endometriosis: back to less aggressive surgery
  • Complications of deep endometriosis surgery: How to avoid them
  • Laparoscopic management of the ovarian endometrioma: Why and how?

POOR OVARIAN RESERVE

  • Oocytes quality deterioration with age: Chromosomes or else?
  • The saga of older age and poor responders: Have we made any progress?
  • Androgens: Do they make any difference?
  • Evidence based Luteal support: Are poor responders different?

IMPLANTATION ISSUES

  • The window of implantation: What do we now?
  • AUGMENT by OvaScience: What is the evidence? what to practitioners need to know about what is being injected
  • Endometrial scratch any solid proofs?

PERICONCEPTIONAL MEDICINE: WHERE REPRODUCTIVE AND FETAL-MATERNAL MEDICINE MEET

  • IVF in the medically complicated patient
  • Periconceptional medicine and the obstetrician
  • Pre-eclampsia: A periconceptional disease

ART/IVF/ LAB WORK

  • In vitro activation of dormant follicles
  • Mitochondrial diseases: technical issues and future therapy
  • improve the sperm selection
  • Quality control in ART
  • Mitochondrial DNA (mtDNA) as biomarker of preimplantation embryo viability

NON INVASIVE GENETIC TESTING OF THE PREIMPLATATION EMBRYOS

  • Blastocoel analysis for PGS and the potential clinical value of mitochondrial screening assays
  • PGS on culture media
  • Mitochondrial DNA (mtDNA) as biomarker of preimplantation embryo viability

TIME LAPSE

  • Debate: Evidence based benefit or simply closed system?
  • Debate: Time lapse: What did we learn so far? Does universal algorithms work?
  • Embryo development on day 3-4 what can be learned
  • Debate: Metabolic needs of human embryos. Nurturing and improving quality of oocytes in the IVF laboratory
  • Towards the best culture system

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GYNECOLOGIC ONCOLOGY

  • Sparing Options in Gynecologic Oncology surgery
  • Fertility-sparing surgery in early-stage cervical cancer
  • Fertility-Sparing Management in Young Endometrial Cancer Patients
  • Assisted reproductive techniques after fertility-sparing treatments
  • Fertility-sparing treatment of endometrial cancer

HPV VACCINES: LIGHTS AND SHADOWS

  • The adoption of HPV vaccines in the world and the axes of assessment of vaccine safety
  • Vaccine confidence and vaccine hesitancy
  • The promises of the HPV vaccines
  • The role of the gynecologists in HPV vaccination

ENDOMETRIAL CANCER

  • The role of lymphadenectomy in the surgical treatment of endometrial cancer
  • Adjuvant therapy of endometrial cancer
  • Lynch syndrome in endometrial cancer patients

OVARIAN CANCER

  • Antiangiogenic treatment in ovarian cancer
  • PARP-inhibition in ovarian cancer patients

MENOPAUSE

  • HRT – WHI authors claim about wrong data interpretation
  • Debates: HRT – Have the risks been overestimated? Will it rebound to pre-WHI era?
  • Debate: Vaginal application of sex steroids: The future in women’s health? What are the limitations?
  • HRT – Oral vs. Transdermal application
  • Prevention of peri-menopausal obesity by diet and life style intervention
  • Fat accumulation around the menopause – the implications
  • Managing obesity: the place of bariatric surgery
  • Exercising in menopause
  • Medical treatment of endometriosis in the perimenopause

BREAST CANCER

  • Progesterone (or hormones) and breast cancer
  • Chemoprevention and prophylactic surgery for breast cancer

ADOLESCENT GYNECOLOGY

  • Neovagina using autologous cultured vagina tissue
  • Vulvovaginoplasty
  • Creation of a neovagina by Davydov’s laparoscopic modified technique in patients with Rokitansky syndrome

OC’s

  • Which estrogen for contraceptive pills
  • WHO guidelines for contraception – how to improve them?
  • Contraceptives and thrombotic risks
  • Contraceptive options for adolescent and the peri-menopausl
  • OC’s are associated with depression?

HRT – DISEASE PREVENTION?

  • Debate: HRT – Cardiovascular risk or prevention?
  • HRT – How to prevent and/or treat (uterine) bleeding problems
    Can we prevent Alzheimer
  • Ovarian tissue re-implantation: The HRT of the  future

OSTEOPORSIS

  • Breast cancer and bone health

PERINATAL LITIGATION

  • Shoulder dystocia and Erb’s palsy: Can we do better?
  • Are the criteria for the association between perinatal events and brain damage valid?
  • Already brain damaged upon admission: can we diagnose?
  • Planned home birth: A challenge of Perinatal Medicine

EMERGENCIES IN THE DELIVERY ROOM

  • Amniotic fluid emboli: Radical change in outlook
  • Intrapartum emergencies in twin birth
  • Debate: Selecting the first line drug for prevention of PPH – Oxytocin / Carbetocin

CONTROVERSIAL ISSUES IN PRETERM BIRTH

  • Is pessary useful in prevention of preterm labor in singleton and twins
  • Steroids for late preterm birth
  • The long-term cardiovascular consequences of SGA
  • Should Progesterone still be used for PTL after the OPPTIMUM negative study?

CS

  • Debate: Is there a minimal advised period before conception after C-Section?
    Proposition: Wait 6 or 12 months before pregnancy
    Opposition: No time limit before new pregnancy after CS
  • Cesarean scar defect – Why some women develop Niche? What are the risks?
  • Surgical management of cesarean scar defect? Laparoscopy or Hysteroscopy
  • Debate: Induction of labour decreases the CS rate
  • Does episiotomy decrease the third and fourth degree tear rate?

FETAL SURGERY

  • Fetoscopic Surgery for Congenital Birth Defects: From Bench to Bedside
  • Diagnosis and treatment of twin-to-twin transfusion syndrome
  • Treatment of diaphragmatic hernia
  • Fetal cardiac interventions: State of the art

INFECTIONS DURING PREGNANCY

  • Zika – Update
  • Strategies for GBS screening, prevention and treatment in the perinatal period (new consensus guidelines)
  • Is there a cure for perinatal HIV-infected children?
  • Bacterial and viral infections during pregnancy increase the risk of autism and schizophrenia in offspring
  • Overview of Viral infection during pregnancy
  • Infectious exposure during pregnancy and delivery and cerebral palsy

STEROIDS FOR LATE PRETERM BIRTH

  • Debate – Steroids for late preterm birth
  • Late effects of CS