Mariano G Buffone Ph.D. earned his Bachelors and master’s degree in Biochemistry from University of Buenos Aires, Argentina where he also obtained his PhD. He then moved to the University of Pennsylvania (Philadelphia, USA) as a postdoctoral fellow under the direction of professors George L. Gerton and Richard M. Schultz.
In 2010, Dr Buffone moved to Buenos Aires and became Assistant Professor at the Instituto de Biologia y Medicina Experimental in Buenos Aires, Argentina where he leads his research team
Since 2015, he assumed his present position as Professor at the same institution. He was recently appointed as Vice Director of the Institute.
His laboratory seeks to understand the complex process of mammalian sperm capacitation with particular emphasis in the process of acrosomal exocytosis. To this end, his lab uses a wide range of approaches that include the analysis of signaling pathways, single cell imaging experiments, super resolution microscopy and in vivo studies. Dr Buffone has also been very active collaborating with several groups in the United States, Japan, Mexico and Argentina.