Dr. Pasquale Patrizio, M.D., M.BE is Professor of Obstetrics, Gynecology, Reproductive Sciences and Chief, Division Reproductive Endocrinology and Infertility (REI) at the University of Miami, Miller School of Medicine. In addition, he is specialized in Andrology and has a Master in Bioethics from the University of Pennsylvania. He is section editor for the American Journal of Obstetrics and Gynecology and Reproductive Biomedicine Online and is editorial board member for the Journal Assisted Reproduction and Genetics. His training and academic appointments in USA include Residency in OB/GYN and Fellowship in REI at the University of California, Irvine (1989-1995); Associate Professor at the Hospital University of Pennsylvania (1996-2003); Professor and Director Yale Fertility Center, Yale University (2004-2021); Chief Division REI University of Miami (2022-current). In 2007 he co-founded the International Society Fertility Preservation(ISFP) and served as President between 2015-2017. On behalf of the American Society of Reproductive Medicine (ASRM) he was executive board member (2007-2011) and Chair (2013-2014) of the Regenerative Medicine Stem Cells Biology Special Interest Group. He served as Chair of the ASRM Fertility Preservation Special Interest Group between 2019-2020.
In 2012 he co-founded Fertilesafe Ltd., a biotechnology company based in Ness Ziona, Israel involved in improving cryopreservation of gametes, embryos, tissue, organs and mesenchymal stem cells and long-term storage by lyophilization. He has authored 9 books, 626 scientific papers (92 book chapters, 236 peer-reviewed publications and 298 published abstracts) and holds 2 issued patents. He is Honorary member of the Italian Society of Fertility and Sterility, Fellow of the International Academy of Human Reproduction and has received many prizes paper awards from both ASRM and ESHRE.
The most significant research, clinical innovation and accomplishments include a) Co-pioneering the technique of microsurgical epididymal sperm aspiration (MESA) and reporting the first two births in the world for men with congenital bilateral absence of the vas deferens (CBAVD); b) Discovery the cause of CBAVD as a mild form of cystic fibrosis; c) Discovery that some cases of male infertility are due to Y-chromosome deletions; d) Pioneering the technique of whole ovary cryopreservation; e) Deciphering molecular mechanisms responsible for Oocyte Aging; f) Studied the sociodemographic pressures leading to elective egg freezing to counteract reproductive aging; g) Establishing the fertility preservation program at Yale (2006) and setting up fertility preservation within the Transgender Health program (2009); h) Understanding the role of embryo mosaicism in implantation and i) Studying human folliculogenesis and endocrine activity across ages using ovaries perfused “ex vivo” in a bioreactor.
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